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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Bayer
Curated by
ChEMBL
Ligand
BDBM50520175
(CHEMBL4451595 | US10894784, Example 135.02)
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Affinity Data
IC50: 1nM
Assay Description:
Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed in sf21 cells using biotin labelled Ahx-GGEEEEYFELVKKKK pe...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Bayer
Curated by
ChEMBL
Ligand
BDBM50520175
(CHEMBL4451595 | US10894784, Example 135.02)
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Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Bayer
Curated by
ChEMBL
Ligand
BDBM50520175
(CHEMBL4451595 | US10894784, Example 135.02)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
(Homo sapiens (Human))
Bayer
Curated by
ChEMBL
Ligand
BDBM50520175
(CHEMBL4451595 | US10894784, Example 135.02)
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Affinity Data
IC50: 35nM
Assay Description:
Inhibition of recombinant full length human C-terminal GST-tagged IKKepsilon expressed in baculovirus expression system using biotin-labelled Ahx-GDE...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human))
Bayer
Curated by
ChEMBL
Ligand
BDBM50520175
(CHEMBL4451595 | US10894784, Example 135.02)
Copy SMILES
Copy InChI
Affinity Data
IC50: 263nM
Assay Description:
Inhibition of recombinant full length human His-tagged CDK9/CyclinT1 expressed in baculovirus expression system using biotin-labelled Ttds-YISPLKSPYK...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Bayer
Curated by
ChEMBL
Ligand
BDBM50520175
(CHEMBL4451595 | US10894784, Example 135.02)
Copy SMILES
Copy InChI
Affinity Data
IC50: 388nM
Assay Description:
Inhibition of recombinant full length human N-terminal His-tagged TBK1 using biotin-labelled Ahx-GDEDFSSFAEPG peptide as substrate preincubated with ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Inhibitor of nuclear factor kappa-B kinase subunit epsilon/Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Bayer
Curated by
ChEMBL
Ligand
BDBM50520175
(CHEMBL4451595 | US10894784, Example 135.02)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.26E+3nM
Assay Description:
Inhibition of IKKepsilon/TBK1 in human MDB-MB-231 cells transduced with lentiviral vector expressing human IRF3 assessed as decrease in poly(I:C)-sti...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Bayer
Curated by
ChEMBL
Ligand
BDBM50520175
(CHEMBL4451595 | US10894784, Example 135.02)
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Affinity Data
IC50: 2.83E+3nM
Assay Description:
Inhibition of recombinant full length human His6-tagged RSK4 expressed in baculovirus infected sf21 cells using biotin labelled Ahx-KKLNRTLSFAEPG pep...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI