Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL

LigandBDBM50535742(CHEMBL4592659)Copy SMILESCopy InChI

Affinity DataEC50:  5.40nMAssay Description:Antagonist activity at integrin alpha4beta1 expressed in human Jurkat cells assessed as reduction in cell adhesion to human VCAM-1 incubated for 40 t...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL

LigandBDBM50535742(CHEMBL4592659)Copy SMILESCopy InChI

Affinity DataEC50:  1.40nMAssay Description:Antagonist activity at integrin alpha4beta7 expressed in human RPMI8866 cells assessed as reduction in cell adhesion to rat MadCAM incubated for 40 t...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI