Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

LigandBDBM50030269(CHEMBL3339220)Copy SMILESCopy InChI

Affinity DataIC50:  25nMAssay Description:Inhibition of cIAP1 BIR2-3 (unknown origin) assessed as inhibition of polarization activity using N-His-Tb-cBir2-3(154-352) by fluorescence polarizat...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

LigandBDBM50030269(CHEMBL3339220)Copy SMILESCopy InChI

Affinity DataIC50:  58nMAssay Description:Inhibition of XIAP-BIR3 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI