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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Baculoviral IAP repeat-containing protein 2
(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by
ChEMBL
Ligand
BDBM50030270
(CHEMBL3339219 | US9783573, Example 23)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of cIAP1 BIR2-3 (unknown origin) assessed as inhibition of polarization activity using N-His-Tb-cBir2-3(154-352) by fluorescence polarizat...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Baculoviral IAP repeat-containing protein 2/Baculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM50030270
(CHEMBL3339219 | US9783573, Example 23)
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Affinity Data
IC50: 4nM
Assay Description:
Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of His-BIR2-3 (125-356, C...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Baculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM50030270
(CHEMBL3339219 | US9783573, Example 23)
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Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of His-BIR3 (241-356, XIA...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by
ChEMBL
Ligand
BDBM50030270
(CHEMBL3339219 | US9783573, Example 23)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of XIAP-BIR3 (unknown origin) by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI