Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL

LigandBDBM50432753(CHEMBL2348613)Copy SMILESCopy InChI

Affinity DataKi:  1.5nMAssay Description:Binding affinity to XIAP linker BIR2-BIR3 domain (unknown origin) after 3 hrs by competitive fluorescence polarization assay in presence of Smac-1FMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL

LigandBDBM50432753(CHEMBL2348613)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Binding affinity to cIAP1 BIR3 domain (unknown origin) after 3 hrs by competitive fluorescence polarization assay in presence of Smac-2FMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL

LigandBDBM50432753(CHEMBL2348613)Copy SMILESCopy InChI

Affinity DataKi:  25nMAssay Description:Binding affinity to cIAP2 BIR3 domain (unknown origin) after 3 hrs by competitive fluorescence polarization assay in presence of Smac-2FMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL

LigandBDBM50432753(CHEMBL2348613)Copy SMILESCopy InChI

Affinity DataIC50:  8.5nMAssay Description:Binding affinity to XIAP linker BIR2-BIR3 domain (unknown origin) after 3 hrs by competitive fluorescence polarization assay in presence of Smac-1FMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL

LigandBDBM50432753(CHEMBL2348613)Copy SMILESCopy InChI

Affinity DataIC50:  75nMAssay Description:Binding affinity to cIAP1 BIR3 domain (unknown origin) after 3 hrs by competitive fluorescence polarization assay in presence of Smac-2FMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL

LigandBDBM50432753(CHEMBL2348613)Copy SMILESCopy InChI

Affinity DataIC50:  95nMAssay Description:Binding affinity to cIAP2 BIR3 domain (unknown origin) after 3 hrs by competitive fluorescence polarization assay in presence of Smac-2FMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI