Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by PDSP Ki Database
LigandPNGBDBM50334460(((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicy...)
Affinity DataKi:  0.370nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50334460(((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicy...)
Affinity DataKi:  19.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035734(CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...)
Affinity DataKi:  157nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50334460(((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicy...)
Affinity DataKi:  362nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035734(CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...)
Affinity DataKi:  596nMAssay Description:Affinity for norepinephrine transporter determined by [3H]nisoxetine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50334460(((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicy...)
Affinity DataKi:  990nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50334460(((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicy...)
Affinity DataKi:  1.73E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by PDSP Ki Database
LigandPNGBDBM50035734(CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by PDSP Ki Database
LigandPNGBDBM50035734(CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...)
Affinity DataIC50:  0.370nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334460(((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicy...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035734(CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...)
Affinity DataIC50:  990nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035734(CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...)
Affinity DataIC50:  991nMAssay Description:Binding affinity at the Norepinephrine transporter in rat frontal cortex by inhibition of 0.5 nM [3H]nisoxetine bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334460(((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicy...)
Affinity DataIC50:  991nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50334460(((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicy...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035734(CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...)
Affinity DataIC50:  1.73E+3nMAssay Description:Binding affinity at the Serotonin transporter in rat midbrain by inhibition of 0.5 nM [3H]-paroxetine bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035734(CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed