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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Interstitial collagenase
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.300nM
Assay Description:
Binding affinity to recombinant MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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Article
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Target
Collagenase 3
(Homo sapiens (Human))
Novartis
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.530nM ΔG°: -52.4kJ/mole IC50: 3.5nM
pH: 7.5 T: 2°C
Assay Description:
Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Novartis
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1nM
Assay Description:
Binding affinity to recombinant MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Inhibition of matrix metalloprotease-1 (MMP-1).
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Novartis
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Inhibition of matrix metalloprotease-13 (MMP-13).
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
University Of Queensland
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
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Affinity Data
Ki: 4nM
Assay Description:
Inhibition of matrix metalloprotease-8 (MMP-8).
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 56nM
Assay Description:
Binding affinity to recombinant MMP3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
University Of Queensland
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 59nM
Assay Description:
Inhibition of matrix metalloprotease-9 (MMP-9).
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
University Of Queensland
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 154nM
Assay Description:
Inhibition of matrix metalloprotease-2 (MMP-2).
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 230nM
Assay Description:
Binding affinity to recombinant TACE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 527nM
Assay Description:
Inhibition of matrix metalloprotease-3 (MMP-3).
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.00E+3nM
Assay Description:
Inhibition of Matrix metalloprotease-1 (MMP1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.30nM
T: 2°C
Assay Description:
Test compounds were serially diluted in deep well plates, and an aliquot of the inhibitor solutions was transferred to a Biomek deep well plate conta...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
University Of Queensland
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40nM
T: 2°C
Assay Description:
Test compounds were serially diluted in deep well plates, and an aliquot of the inhibitor solutions was transferred to a Biomek deep well plate conta...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Novartis
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.40nM
Assay Description:
Inhibitory activity against matrix metalloprotease-13 (MMP13)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
University Of Queensland
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
IC50: 58nM
Assay Description:
Inhibitory activity against matrix metalloprotease-9 (MMP9)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
IC50: 87nM
T: 2°C
Assay Description:
Test compounds were serially diluted in deep well plates, and an aliquot of the inhibitor solutions was transferred to a Biomek deep well plate conta...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
University Of Queensland
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
IC50: 154nM
Assay Description:
Inhibitory activity against matrix metalloprotease-2 (MMP2)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
IC50: 527nM
Assay Description:
Inhibitory activity against matrix metalloprotease-3 (MMP3)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM30344
(Cipemastat | Trocade)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of LPS/interferon gamma-stimulated TNFalpha release from HPBMC
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI