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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Serine/threonine-protein kinase mTOR
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
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Affinity Data
IC50: 3nM
Assay Description:
Inhibition of mTOR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
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Affinity Data
IC50: 170nM
Assay Description:
Inhibition of human VPS34
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
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Affinity Data
IC50: 437nM
Assay Description:
Inhibition of PI3K C2beta
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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Target
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
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Affinity Data
IC50: 922nM
Assay Description:
Inhibition of P110alpha/p85alpha
More data for this Ligand-Target Pair
Target Info
PDB
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antibodypedia
antibodypedia
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Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.11E+3nM
Assay Description:
Inhibition of PI3K C2alpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Target
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
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Affinity Data
IC50: 1.17E+3nM
Assay Description:
Inhibition of P110delta/p85alpha
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
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CHEMBL
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In Depth
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Article
PubMed
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
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Affinity Data
IC50: 1.17E+3nM
Assay Description:
Inhibition of P110gamma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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B.MOAD
DrugBank
antibodypedia
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Target
Phosphatidylinositol 4-kinase beta
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
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Affinity Data
IC50: 3.44E+3nM
Assay Description:
Inhibition of PI4K beta
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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CHEMBL
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PubMed
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Target
Phosphatidylinositol 4-kinase alpha
(Homo sapiens (Human))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of PI4K alpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase mTOR
(Mus musculus (Mouse))
Dana-Farber Cancer Institute
Curated by
ChEMBL
Ligand
BDBM50346961
(CHEMBL1795875)
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Affinity Data
EC50: 5nM
Assay Description:
Inhibition of mTOR-dependent S6K phosphorylation at T389 residue in MEF cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Patents
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In Depth
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Article
PubMed
Copy BDB DOI