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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
Eli Lilly
US Patent
Ligand
BDBM318030
(8-Methyl-2-[4-(o- tolylmethyl)piperazin-1-yl]- 3,5...)
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Affinity Data
IC50: 12.2nM
Assay Description:
The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
Eli Lilly
US Patent
Ligand
BDBM318030
(8-Methyl-2-[4-(o- tolylmethyl)piperazin-1-yl]- 3,5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15.2nM
Assay Description:
The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
Eli Lilly
US Patent
Ligand
BDBM318030
(8-Methyl-2-[4-(o- tolylmethyl)piperazin-1-yl]- 3,5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.74E+4nM
Assay Description:
The Poly ADP-ribose polymerase 1(PARP1) assay is an ELISA which detects poly ADP ribose incorporated into plate-bound histone protein in a 384-well f...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI