Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318023(8-Methyl-2-[4-[(5- methylpyrimidin-2- yl)methyl]pi...)
Affinity DataIC50:  67.6nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318023(8-Methyl-2-[4-[(5- methylpyrimidin-2- yl)methyl]pi...)
Affinity DataIC50:  81.5nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318023(8-Methyl-2-[4-[(5- methylpyrimidin-2- yl)methyl]pi...)
Affinity DataIC50:  7.22E+3nMAssay Description:The Poly ADP-ribose polymerase 1(PARP1) assay is an ELISA which detects poly ADP ribose incorporated into plate-bound histone protein in a 384-well f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent