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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataKi:  100nMAssay Description:Inhibitory activity against HIV-1 Y188L reverse transcriptase.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataKi:  101nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataIC50:  230nMAssay Description:Antagonist activity at p38 MAPK alpha (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataIC50:  282nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataIC50:  2.61E+3nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537600(CHEMBL4129018 | US11149020, Compound 27 (MW-150))
Affinity DataIC50:  2.80E+3nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
In DepthDetails US Patent