Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM400808(QL-XII-91 | US10000483, Compound I-17)
Affinity DataIC50:  155nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM400808(QL-XII-91 | US10000483, Compound I-17)
Affinity DataIC50:  155nMAssay Description:Inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM400808(QL-XII-91 | US10000483, Compound I-17)
Affinity DataIC50:  399nMAssay Description:Purified BMX was mixed with substrate (FAK or Bmxtides), kinase buffer (final 20 mM HEPES, pH 7.5, 10 mM MgCl2, 20 mM β-glycerophosphate, 1 mM d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM400808(QL-XII-91 | US10000483, Compound I-17)
Affinity DataIC50:  399nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM400808(QL-XII-91 | US10000483, Compound I-17)
Affinity DataIC50:  399nMAssay Description:Inhibition of recombinant full length His-tagged human BMX expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM400808(QL-XII-91 | US10000483, Compound I-17)
Affinity DataIC50:  516nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM400808(QL-XII-91 | US10000483, Compound I-17)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of recombinant GST-tagged human JAK3 expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM400808(QL-XII-91 | US10000483, Compound I-17)
Affinity DataIC50:  5.58E+3nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM400808(QL-XII-91 | US10000483, Compound I-17)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length His-tagged human BLK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed