Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 18 hits in this display   

TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PKCepsilon by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  17nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  33nMAssay Description:Inhibition of PKCeta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  260nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  730nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  800nMAssay Description:Inhibition of PKCbeta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PKCzeta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed