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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
18
hits in this display
Target
Protein kinase C theta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: 0.280nM
Assay Description:
Inhibition of human PKCtheta by IMAP fluorescence polarization technology
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Article
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Target
Protein kinase C epsilon type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: 2.5nM
Assay Description:
Inhibition of PKCepsilon by IMAP fluorescence polarization technology
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Protein kinase C delta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: 17nM
Assay Description:
Inhibition of PKCdelta by IMAP fluorescence polarization technology
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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Article
PubMed
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Target
Protein kinase C theta type
(Mus musculus)
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: 21nM
Assay Description:
Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Protein kinase C eta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: 33nM
Assay Description:
Inhibition of PKCeta by IMAP fluorescence polarization technology
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: 260nM
Assay Description:
Inhibition of Lck
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: 730nM
Assay Description:
Inhibition of Lyn
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
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Article
PubMed
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Target
Protein kinase C beta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: 800nM
Assay Description:
Inhibition of PKCbeta by IMAP fluorescence polarization technology
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: >9.00E+3nM
Assay Description:
Inhibition of ROCK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: >9.00E+3nM
Assay Description:
Inhibition of MK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
UniProtKB/SwissProt
B.MOAD
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GoogleScholar
Ligand Info
CHEMBL
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Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2D6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C19
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP3A4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein kinase C zeta type
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50302042
(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of PKCzeta by IMAP fluorescence polarization technology
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI