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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  14nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  692nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  770nMAssay Description:Inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50090259((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed