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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Neutrophil collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50090259
((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
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Affinity Data
IC50: 0.770nM
Assay Description:
Inhibition of matrix metalloprotease-8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Macrophage metalloelastase
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM50090259
((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
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Affinity Data
IC50: 8.10nM
Assay Description:
Inhibition of MMP12
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage metalloelastase
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM50090259
((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
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Copy InChI
Affinity Data
IC50: 8.20nM
Assay Description:
Inhibition of matrix metalloprotease-12
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50090259
((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
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Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of matrix metalloprotease-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50090259
((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14nM
Assay Description:
Inhibition of Matrix metalloprotease-13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50090259
((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Inhibitory activity against matrix metalloprotease-13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM50090259
((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 692nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM50090259
((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 770nM
Assay Description:
Inhibitory activity against matrix metalloprotease-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50090259
((4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcar...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+3nM
Assay Description:
Inhibition of matrix metalloprotease-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI