Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50073831((4-Benzyl-benzyl)-[3-cyclobutyl-2-((R)-2,2-dimethy...)Copy SMILESCopy InChI

Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant Matrix metalloproteinase-13 (MMP-13)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50073831((4-Benzyl-benzyl)-[3-cyclobutyl-2-((R)-2,2-dimethy...)Copy SMILESCopy InChI

Affinity DataIC50:  180nMAssay Description:Inhibitory activity against recombinant matrix metalloprotease-1 (MMP-1).More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI