Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50:  257nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50:  257nMAssay Description:Inhibition of recombinant human full length MMP13 expressed in mouse NS0 cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human MMP2 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP9 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human MMP8 expressed in mouse NS0 cells using Knight substrate preincubated for 30 mins followed by substrate addition by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human MMP9 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Graz University Of Technology

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human MMP14 expressed in Escherichia coli using fTHP-15 as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Graz University Of Technology

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: >5.00E+3nMAssay Description:Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the KidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NS0 cells using Knight substrate preincubated for 30 mins followed by substrate addition by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed