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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50386892
(CHEMBL2048512 | MMP inhibitor III)
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Affinity Data
IC50: 3.60nM
Assay Description:
Inhibition of human recombinant MMP2 catalytic domain incubated for 20 mins by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Interstitial collagenase
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50386892
(CHEMBL2048512 | MMP inhibitor III)
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Affinity Data
IC50: 4.10nM
Assay Description:
Inhibition of human recombinant MMP1 catalytic domain incubated for 20 mins by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50386892
(CHEMBL2048512 | MMP inhibitor III)
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Affinity Data
IC50: 6.40nM
Assay Description:
Inhibition of human recombinant MMP13 catalytic domain incubated for 20 mins by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Macrophage metalloelastase
(Homo sapiens (Human))
East China University Of Science And Technology
Curated by
ChEMBL
Ligand
BDBM50386892
(CHEMBL2048512 | MMP inhibitor III)
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Affinity Data
IC50: 8.20nM
Assay Description:
Inhibition of human recombinant MMP12 catalytic domain incubated for 20 mins by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Interstitial collagenase [100-268]
(Homo sapiens (Human))
East China University of Science and Technology
Ligand
BDBM50386892
(CHEMBL2048512 | MMP inhibitor III)
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Affinity Data
IC50: 10nM
pH: 7.5
Assay Description:
The activity of cd-MMP-1 was measured using a fluorescence-based assay. It was performed in white 96-well half area microplate (Greiner) in a final v...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Lethal factor
(Bacillus anthracis)
Microbiotix
Curated by
ChEMBL
Ligand
BDBM50444768
(CHEMBL3099019)
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Affinity Data
IC50: 7.00E+3nM
Assay Description:
Inhibition of Bacillus anthracis lethal factor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI