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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM117012
(US8637532, 739)
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Affinity Data
IC50: 0.600nM
pH: 7.5 T: 2°C
Assay Description:
P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
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In Depth
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US Patent
PDB
3D Structure (crystal)
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Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by
ChEMBL
Ligand
BDBM117012
(US8637532, 739)
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Affinity Data
IC50: 4nM
Assay Description:
Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mob...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Aurora kinase B/Inner centromere protein
(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by
ChEMBL
Ligand
BDBM117012
(US8637532, 739)
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Affinity Data
IC50: 4nM
Assay Description:
Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by
ChEMBL
Ligand
BDBM117012
(US8637532, 739)
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Affinity Data
IC50: 3.60E+3nM
Assay Description:
Inhibition of CYP2C9 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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