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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Affinity Data
IC50: 0.5nM
Assay Description:
Inhibition of Lck by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Affinity Data
IC50: 9nM
Assay Description:
Inhibition of p38-alpha by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Affinity Data
IC50: 17nM
Assay Description:
Inhibition of Src by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 17nM
Assay Description:
Inhibition of KDR by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Copy InChI
Affinity Data
IC50: 868nM
Assay Description:
Inhibition of Jak3 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Affinity Data
IC50: 1.11E+3nM
Assay Description:
Inhibition of Syk by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Affinity Data
IC50: 2.73E+3nM
Assay Description:
Inhibition of Tyk2 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Affinity Data
IC50: 3.33E+3nM
Assay Description:
Inhibition of Btk by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of Aurora1 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of JNK3 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of Itk by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of JNK1 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of Aurora2 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cAMP-dependent protein kinase catalytic subunit beta
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of PKAbeta by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of PKBalpha by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 5
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of CDK5 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of Pak2 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of JNK2 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of MSK1 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase ZAP-70
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50194671
(4-methyl-3-(2-(methylamino)quinazolin-6-yl)-N-(2-(...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Inhibition of Zap70 by HTRF kinase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI