Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent

LigandBDBM451146(US10676499, Example 18)Copy SMILESCopy InChI

Affinity DataKi:  180nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent

LigandBDBM451146(US10676499, Example 18)Copy SMILESCopy InChI

Affinity DataKd:  160nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI