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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Diaxonhit
US Patent
Ligand
BDBM50434347
(CHEMBL2386753 | US9446044, 48)
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Affinity Data
IC50: 1.65nM
pH: 7.5 T: 2°C
Assay Description:
The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Diaxonhit
US Patent
Ligand
BDBM50434347
(CHEMBL2386753 | US9446044, 48)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70nM
Assay Description:
Inhibition of recombinant DYRK1A (unknown origin) after 120 mins in presence of [33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Diaxonhit
US Patent
Ligand
BDBM50434347
(CHEMBL2386753 | US9446044, 48)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20nM
pH: 7.5 T: 2°C
Assay Description:
The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Diaxonhit
US Patent
Ligand
BDBM50434347
(CHEMBL2386753 | US9446044, 48)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20nM
Assay Description:
Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATP
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Diaxonhit
US Patent
Ligand
BDBM50434347
(CHEMBL2386753 | US9446044, 48)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47nM
Assay Description:
Inhibition of DYRK1A (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3
(Homo sapiens (Human))
University Of Louisiana At Lafayette
Curated by
ChEMBL
Ligand
BDBM50434347
(CHEMBL2386753 | US9446044, 48)
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Affinity Data
IC50: 660nM
Assay Description:
Inhibition of GSK3alpha/beta (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 1
(Homo sapiens (Human))
University Of Louisiana At Lafayette
Curated by
ChEMBL
Ligand
BDBM50434347
(CHEMBL2386753 | US9446044, 48)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CDK1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 5
(Homo sapiens (Human))
University Of Louisiana At Lafayette
Curated by
ChEMBL
Ligand
BDBM50434347
(CHEMBL2386753 | US9446044, 48)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CDK5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI