Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Diaxonhit

US Patent
LigandPNGBDBM50434347(CHEMBL2386753 | US9446044, 48)
Affinity DataIC50:  1.65nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Diaxonhit

US Patent
LigandPNGBDBM50434347(CHEMBL2386753 | US9446044, 48)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant DYRK1A (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Diaxonhit

US Patent
LigandPNGBDBM50434347(CHEMBL2386753 | US9446044, 48)
Affinity DataIC50:  4.20nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Diaxonhit

US Patent
LigandPNGBDBM50434347(CHEMBL2386753 | US9446044, 48)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Diaxonhit

US Patent
LigandPNGBDBM50434347(CHEMBL2386753 | US9446044, 48)
Affinity DataIC50:  47nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50434347(CHEMBL2386753 | US9446044, 48)
Affinity DataIC50:  660nMAssay Description:Inhibition of GSK3alpha/beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50434347(CHEMBL2386753 | US9446044, 48)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50434347(CHEMBL2386753 | US9446044, 48)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed