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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Egl nine homolog 1
(Homo sapiens (Human))
Akebia Therapeutics
US Patent
Ligand
BDBM107713
(US8598210, Table XV, 19 | US8722895, 19: ({3-Hydro...)
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Affinity Data
IC50: 2.60E+3nM
Assay Description:
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALDI-T...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Egl nine homolog 1
(Homo sapiens (Human))
Akebia Therapeutics
US Patent
Ligand
BDBM107713
(US8598210, Table XV, 19 | US8722895, 19: ({3-Hydro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.60E+3nM
T: 2°C
Assay Description:
The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALDI-T...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Vascular endothelial growth factor A
(Homo sapiens (Human))
Akebia Therapeutics
US Patent
Ligand
BDBM107713
(US8598210, Table XV, 19 | US8722895, 19: ({3-Hydro...)
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Copy InChI
Affinity Data
EC50: >1.00E+5nM
Assay Description:
HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI