Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMonoglyceride lipase(Mus musculus (mouse))
Abide Therapeutics

US Patent

LigandBDBM280525(US10030020, Example 70)Copy SMILESCopy InChI

Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetMonoacylglycerol lipase ABHD2(Mus musculus (Mouse))
Abide Therapeutics

US Patent

LigandBDBM280525(US10030020, Example 70)Copy SMILESCopy InChI

Affinity DataIC50:  550nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...More data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Abide Therapeutics

US Patent

LigandBDBM280525(US10030020, Example 70)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI