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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Macrophage metalloelastase
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM28469
((2S)-2-({12-[(methoxycarbonyl)amino]-8-oxatricyclo...)
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Affinity Data
IC50: 2nM
pH: 7.5 T: 2°C
Assay Description:
The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage metalloelastase
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM28469
((2S)-2-({12-[(methoxycarbonyl)amino]-8-oxatricyclo...)
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Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibition of human recombinant MMP12
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM28469
((2S)-2-({12-[(methoxycarbonyl)amino]-8-oxatricyclo...)
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Affinity Data
IC50: 60nM
Assay Description:
Inhibition of human MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM28469
((2S)-2-({12-[(methoxycarbonyl)amino]-8-oxatricyclo...)
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Copy InChI
Affinity Data
IC50: 120nM
Assay Description:
Inhibition of human recombinant MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM28469
((2S)-2-({12-[(methoxycarbonyl)amino]-8-oxatricyclo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 120nM
Assay Description:
The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI