Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
Caspase-7(Homo sapiens (Human))Westfalische Wilhelms-Universitat
Curated by ChEMBL
BDBM50258700((S)-1-(3,4-Dihydroxybutyl)-5-[1-(2-methoxymethylpy...)IC50: 61nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
Caspase-7(Homo sapiens (Human))Westfalische Wilhelms-Universitat
Curated by ChEMBL
Caspase-3(Homo sapiens (Human))Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
Caspase-7(Homo sapiens (Human))Westfalische Wilhelms-Universitat
Curated by ChEMBL
IC50: 128nMAssay Description:Inhibition of human recombinant caspase-7 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
Caspase-3(Homo sapiens (Human))Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
IC50: 187nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
Caspase-3(Homo sapiens (Human))Westf£Lische Wilhelms-Universit£T M£Nster
Curated by ChEMBL
BDBM50258700((S)-1-(3,4-Dihydroxybutyl)-5-[1-(2-methoxymethylpy...)
IC50: 275nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
Caspase-6(Homo sapiens (Human))Westfalische Wilhelms-Universitat
Curated by ChEMBL
BDBM50258700((S)-1-(3,4-Dihydroxybutyl)-5-[1-(2-methoxymethylpy...)
IC50: >5.00E+5nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
Caspase-1(Homo sapiens (Human))Westfalische Wilhelms-Universitat
Curated by ChEMBL
BDBM50258700((S)-1-(3,4-Dihydroxybutyl)-5-[1-(2-methoxymethylpy...)
IC50: >5.00E+5nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair