Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 4 hits in this display
Caspase-7(Homo sapiens (Human))Westfalische Wilhelms-Universitat
Curated by ChEMBL
BDBM50258695((S)-1-[4-(2-Bromo-1-fluoroethyl)benzyl]-5-[1-(2-me...)IC50: 16nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
Caspase-3(Homo sapiens (Human))Westfalische Wilhelms-Universitat
Curated by ChEMBL
BDBM50258695((S)-1-[4-(2-Bromo-1-fluoroethyl)benzyl]-5-[1-(2-me...)
IC50: 43nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
Caspase-6(Homo sapiens (Human))Westfalische Wilhelms-Universitat
Curated by ChEMBL
BDBM50258695((S)-1-[4-(2-Bromo-1-fluoroethyl)benzyl]-5-[1-(2-me...)
IC50: >5.00E+5nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
Caspase-1(Homo sapiens (Human))Westfalische Wilhelms-Universitat
Curated by ChEMBL
BDBM50258695((S)-1-[4-(2-Bromo-1-fluoroethyl)benzyl]-5-[1-(2-me...)
IC50: >5.00E+5nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair