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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173222
((S)-2-{4'-[(4-methoxy-3,5-dimethyl-benzofuran-2-ca...)
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Affinity Data
IC50: 4.90nM
Assay Description:
Inhibitory concentration against MMP-13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Neutrophil collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173222
((S)-2-{4'-[(4-methoxy-3,5-dimethyl-benzofuran-2-ca...)
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Affinity Data
IC50: 52nM
Assay Description:
Inhibitory concentration against MMP-8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173222
((S)-2-{4'-[(4-methoxy-3,5-dimethyl-benzofuran-2-ca...)
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Affinity Data
IC50: 442nM
Assay Description:
Inhibitory concentration against MMP-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Matrilysin
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173222
((S)-2-{4'-[(4-methoxy-3,5-dimethyl-benzofuran-2-ca...)
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Copy InChI
Affinity Data
IC50: 534nM
Assay Description:
Inhibitory concentration against MMP-7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173222
((S)-2-{4'-[(4-methoxy-3,5-dimethyl-benzofuran-2-ca...)
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Affinity Data
IC50: 1.61E+3nM
Assay Description:
Inhibitory concentration against MMP-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
A disintegrin and metalloproteinase with thrombospondin motifs 4
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173222
((S)-2-{4'-[(4-methoxy-3,5-dimethyl-benzofuran-2-ca...)
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Affinity Data
IC50: 8.60E+3nM
Assay Description:
Inhibitory concentration against Aggrecanase 1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173222
((S)-2-{4'-[(4-methoxy-3,5-dimethyl-benzofuran-2-ca...)
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Affinity Data
IC50: 1.50E+4nM
Assay Description:
Inhibitory concentration against MMP-14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173222
((S)-2-{4'-[(4-methoxy-3,5-dimethyl-benzofuran-2-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.51E+4nM
Assay Description:
Inhibition of MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50173222
((S)-2-{4'-[(4-methoxy-3,5-dimethyl-benzofuran-2-ca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.71E+4nM
Assay Description:
Inhibitory concentration against MMP-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI