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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM191769(US11608309, Compound 6 | US9187406, Compound 6)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCollagenase 3(Homo sapiens (Human))
The Research Foundation of State University of New York

US Patent
LigandPNGBDBM191769(US11608309, Compound 6 | US9187406, Compound 6)
Affinity DataIC50: <1.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191769(US11608309, Compound 6 | US9187406, Compound 6)
Affinity DataIC50:  8.50E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))
The Research Foundation For The State University of New York

US Patent
LigandPNGBDBM191769(US11608309, Compound 6 | US9187406, Compound 6)
Affinity DataIC50:  8.50E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails US Patent