Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 13 hits in this display
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
IC50: 2.90E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
IC50: 2.90E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
IC50: 2.90E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
IC50: 8.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
IC50: 8.50E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
Collagenase 3(Homo sapiens (Human))The Research Foundation of State University of New York
US Patent
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
IC50: 1.10E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Collagenase 3(Homo sapiens (Human))The Research Foundation of State University of New York
US Patent
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
IC50: 1.10E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Collagenase 3(Homo sapiens (Human))The Research Foundation of State University of New York
US Patent
BDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)
IC50: 1.10E+5nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair