Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 22 hits in this display
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
IC50: 23nMAssay Description:Inhibition of tracer 5 binding to human N-terminal nano luciferase-fused GAK expressed in HEK293 cells measured after 2 hrs by nanoBRET assayMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 11nMAssay Description:Binding affinity to human wild type partial length GAK (G13 to Y338 residues) expressed in bacterial expression system by KinomeScan methodMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 1.30E+3nMAssay Description:Binding affinity to human wild type partial length ACVR1 (C188 to C509 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 280nMAssay Description:Binding affinity to human wild type partial length BMPR1B (D178 to L502 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 1.30E+3nMAssay Description:Binding affinity to human wild type partial length EphA1 (V588 to I913 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 560nMAssay Description:Binding affinity to human wild type partial length EphA8 (Q608 to C920 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 130nMAssay Description:Binding affinity to human wild type partial length EphB6 (Q634 to P948 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 350nMAssay Description:Binding affinity to wild-type human partial length LCK (R207 to P509 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 430nMAssay Description:Binding affinity to human wild type partial length MEK5 (L98 to P448 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 190nMAssay Description:Binding affinity to wild-type human partial length RIPK2 (M1 to K310 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
BDBM6511(4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...)
Kd: 410nMAssay Description:Binding affinity to wild-type human partial length EGFR (R669 to V1011 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair