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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM278177
((R)-2-(5-hydroxy-2-oxopiperidin-1-yl)-5-(4-((3-met...)
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Affinity Data
IC50: 152nM
Assay Description:
Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM278177
((R)-2-(5-hydroxy-2-oxopiperidin-1-yl)-5-(4-((3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 174nM
Assay Description:
Enzymatic activity of hJAK2 was measured using a LANCE homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that monitors...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM278177
((R)-2-(5-hydroxy-2-oxopiperidin-1-yl)-5-(4-((3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 270nM
Assay Description:
Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM278177
((R)-2-(5-hydroxy-2-oxopiperidin-1-yl)-5-(4-((3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.52E+5nM
pH: 7.0
Assay Description:
Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM278177
((R)-2-(5-hydroxy-2-oxopiperidin-1-yl)-5-(4-((3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.74E+5nM
pH: 7.5
Assay Description:
Enzymatic activity of hJAK2 was measured using a LANCE homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that monitors...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM278177
((R)-2-(5-hydroxy-2-oxopiperidin-1-yl)-5-(4-((3-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70E+5nM
pH: 7.0
Assay Description:
Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI