Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 21 hits in this display
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Ki: 600nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Ki: 2.54E+3nMAssay Description:Competitive inhibition of G6PD (unknown origin) using varying concentrations of G6P and NADP+ as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Ki: 9.94E+3nMAssay Description:Non-competitive inhibition of G6PD (unknown origin) using varying concentrations of G6P and NADP+ as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
IC50: 3.78E+3nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
IC50: 1.73E+4nMAssay Description:Inhibition of OCT2(unknown origin)-mediated ASP+ uptake in HEK293 cells expressing OCT2 using ASP+ as substrate incubated for 5 minsMore data for this Ligand-Target Pair
Genome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))Umdnj-New Jersey Medical School
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
IC50: 3.84E+4nMAssay Description:Inhibition of OCT1(unknown origin)-mediated ASP+ uptake in HEK293 cells expressing OCT1 using ASP+ as substrate incubated for 5 minsMore data for this Ligand-Target Pair
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Kd: 3.64E+3nMAssay Description:Binding affinity to G6PD (unknown origin) assessed as equilibrium dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Kd: 2.82E+3nMAssay Description:Binding affinity to CM5 sensor chip immobilised EED (unknown origin) assessed as dissociation constant incubated for 270 secs by SPR analysisMore data for this Ligand-Target Pair
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
BDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)