Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056680(CHEMBL3341794)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056680(CHEMBL3341794)
Affinity DataIC50:  20nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056680(CHEMBL3341794)
Affinity DataIC50:  30nMAssay Description:Inhibition of purified human ALK5 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056680(CHEMBL3341794)
Affinity DataIC50:  760nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed