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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 3(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50587939(CHEMBL5176029)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using Ac-Leu-Gly-Lys (Ac)-AMC as substrate pretreated for 5 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetHistone deacetylase 1(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50587939(CHEMBL5176029)
Affinity DataIC50:  9.04E+3nMAssay Description:Inhibition of full length recombinant human HDAC1 (1 to 482 residues) expressed in Baculovirus system using Ac-Leu-Gly-Lys (Ac)-AMC as substrate pret...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50587939(CHEMBL5176029)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of full length C-terminal his-tagged human recombinant HDAC8 (142 to 143 residues) expressed in baculovirus in Sf9 insect cells using Ac-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTubulin beta chain(Sus scrofa)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50587939(CHEMBL5176029)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50587939(CHEMBL5176029)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of full length N-terminal GST-tagged human recombinant HDAC6 (1 to 1215 residues) expressed in Baculovirus infected Sf9 cells using Ac-Leu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50587939(CHEMBL5176029)
Affinity DataIC50:  4.27E+4nMAssay Description:Inhibition of full length N-terminal GST-tagged human recombinant HDAC7 (501 to 952 residues) expressed in Baculovirus system using Ac-Leu-Gly-Lys (A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed