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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
University Of Perugia
Curated by
ChEMBL
Ligand
BDBM50468269
(CHEMBL4285233)
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Affinity Data
IC50: 31nM
Assay Description:
Inhibition of N-terminal GST-tagged human TNKS1 expressed in Sf9 cells incubated for 1 hr by histone ribosylation assay
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3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
University Of Perugia
Curated by
ChEMBL
Ligand
BDBM50468269
(CHEMBL4285233)
Copy SMILES
Copy InChI
Affinity Data
IC50: 31nM
Assay Description:
Antagonistic activity against histamine H3 receptor in guinea pig ileum
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Target Info
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3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Perugia
Curated by
ChEMBL
Ligand
BDBM50468269
(CHEMBL4285233)
Copy SMILES
Copy InChI
Affinity Data
IC50: 36nM
Assay Description:
Inhibition of N-terminal GST-tagged human TNKS2 expressed in Sf9 cells incubated for 1 hr by histone ribosylation assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Perugia
Curated by
ChEMBL
Ligand
BDBM50468269
(CHEMBL4285233)
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Copy InChI
Affinity Data
IC50: 36nM
Assay Description:
Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cells
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Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
University Of South Australia
Curated by
ChEMBL
Ligand
BDBM50468269
(CHEMBL4285233)
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Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibition of PARP1 (unknown origin) at 10 uM relative to control
More data for this Ligand-Target Pair
Target Info
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MMDB
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