Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50468269(CHEMBL4285233)
Affinity DataIC50:  31nMAssay Description:Inhibition of N-terminal GST-tagged human TNKS1 expressed in Sf9 cells incubated for 1 hr by histone ribosylation assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50468269(CHEMBL4285233)
Affinity DataIC50:  31nMAssay Description:Antagonistic activity against histamine H3 receptor in guinea pig ileumMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50468269(CHEMBL4285233)
Affinity DataIC50:  36nMAssay Description:Inhibition of N-terminal GST-tagged human TNKS2 expressed in Sf9 cells incubated for 1 hr by histone ribosylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50468269(CHEMBL4285233)
Affinity DataIC50:  36nMAssay Description:Effect on IP3 turnover by phospholipaseC positively linked to human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of South Australia

Curated by ChEMBL
LigandPNGBDBM50468269(CHEMBL4285233)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of PARP1 (unknown origin) at 10 uM relative to controlMore data for this Ligand-Target Pair
In DepthDetails PubMed