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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
Aristotle University
Ligand
BDBM24529
((2Z,5E)-2-(1,2-benzothiazol-3-ylimino)-5-[(4-metho...)
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Affinity Data
Ki: 2.28E+4nM ΔG°: -26.5kJ/mole
pH: 7.0 T: 2°C
Assay Description:
SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM24529
((2Z,5E)-2-(1,2-benzothiazol-3-ylimino)-5-[(4-metho...)
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Affinity Data
IC50: 36nM
Assay Description:
Inhibition of MMP13 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Institute Of Technology
Curated by
ChEMBL
Ligand
BDBM24529
((2Z,5E)-2-(1,2-benzothiazol-3-ylimino)-5-[(4-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 36nM
pH: 7.0 T: 2°C
Assay Description:
The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI