Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 11 hits in this display
IC50: 1.81E+3nMAssay Description:Inhibition of human HDAC11 using Acetyl-Lys (trifluoroacetyl)-AMC) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
IC50: 2.69E+3nMAssay Description:Inhibition of human HDAC10 using Acetyl-Lys (trifluoroacetyl)-AMC) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
IC50: 1.40E+4nMAssay Description:Inhibition of human DNMT1 using Poly(dI-dC) as substrate incubated for 1 hr in presence of [3H]-SAM by filter binding methodMore data for this Ligand-Target Pair
IC50: 7.40E+4nMAssay Description:Inhibition of human DNMT3a using lambda DNA as substrate incubated for 1 hr in presence of [3H]-SAM by filter binding methodMore data for this Ligand-Target Pair
EC50: 1.42E+5nMAssay Description:Inhibition of human G9a using core histone H3 (1 to 21 residues) as substrate incubated for 1 hr in presence of [3H]-SAM by filter binding methodMore data for this Ligand-Target Pair
EC50: 7.50E+3nMAssay Description:Inhibition of HDAC1/2/3 in human KMS-12-BM cells assessed as increase in Ac-H3 level incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair