Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie

Curated by ChEMBL

LigandBDBM50592361(CHEMBL5173199)Copy SMILESCopy InChI

Affinity DataEC50:  2.11E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie

Curated by ChEMBL

LigandBDBM50592361(CHEMBL5173199)Copy SMILESCopy InChI

Affinity DataEC50:  2.11E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie

Curated by ChEMBL

LigandBDBM50592361(CHEMBL5173199)Copy SMILESCopy InChI

Affinity DataEC50:  241nMAssay Description:Potentiation of homozygous CFTR F508del mutant in human HBE cells by trans-epithelial current clamp assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie

Curated by ChEMBL

LigandBDBM50592361(CHEMBL5173199)Copy SMILESCopy InChI

Affinity DataEC50:  1.78E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie

Curated by ChEMBL

LigandBDBM50592361(CHEMBL5173199)Copy SMILESCopy InChI

Affinity DataEC50:  1.78E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI