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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Macrophage metalloelastase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
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Affinity Data
IC50: 0.200nM
Assay Description:
Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
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Affinity Data
IC50: 0.800nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage metalloelastase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.850nM
Assay Description:
Inhibition of autoactivated human pro-MMP12 after 1 hr preincubation by fluorometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage metalloelastase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.890nM
Assay Description:
Inhibition of autoactivated human pro-MMP12 after 30 mins preincubation by fluorometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
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Affinity Data
IC50: 3.5nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
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Affinity Data
IC50: 4.10nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
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Affinity Data
IC50: 5.10nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
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Affinity Data
IC50: 21nM
Assay Description:
Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-16
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 32nM
Assay Description:
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage metalloelastase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 200nM
Assay Description:
Inhibition of MMP12 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299051
(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.50E+3nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI