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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Punjabi University
Curated by
ChEMBL
Ligand
BDBM85573
(7-Hydroxy-flavone, 5h)
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Affinity Data
IC50: 35nM
Assay Description:
Inhibition of rat brain AChE using acetylthiocholine iodide as substrate by spectroscopic method
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Target Info
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MMDB
KEGG
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B.MOAD
GoogleScholar
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MMDB
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM85573
(7-Hydroxy-flavone, 5h)
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Affinity Data
IC50: 450nM
Assay Description:
Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...
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Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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MMDB
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In Depth
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3D Structure (crystal)
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Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM85573
(7-Hydroxy-flavone, 5h)
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Affinity Data
IC50: 560nM
Assay Description:
Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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MMDB
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PC sid
PDB
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Aromatase
(Homo sapiens (Human))
Cardiff University
Ligand
BDBM85573
(7-Hydroxy-flavone, 5h)
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Affinity Data
IC50: 1.00E+5nM
T: 2°C
Assay Description:
The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MMDB
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In Depth
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Article
PubMed
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Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM85573
(7-Hydroxy-flavone, 5h)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant ARTD1 by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI