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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Tyrosine-protein kinase SYK
(Human)
Glaxosmithkline R&D
Curated by
ChEMBL
Ligand
BDBM50467635
(CHEMBL4288596)
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Affinity Data
IC50: 398nM
Assay Description:
Inhibition of recombinant human N-terminal His6-tagged SYK expressed in baculovirus expression system using Biotin-AAAEEIYGEI as substrate after 60 m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Aurora kinase B/Inner centromere protein
(Human)
Glaxosmithkline R&D
Curated by
ChEMBL
Ligand
BDBM50467635
(CHEMBL4288596)
Copy SMILES
Copy InChI
Affinity Data
IC50: <2.51E+4nM
Assay Description:
Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI