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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Collagenase 3
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM30359
(BOC-piperidinyl glycine derivative, 34)
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Affinity Data
IC50: 0.398nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM30359
(BOC-piperidinyl glycine derivative, 34)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.400nM
Assay Description:
In vitro inhibitory activity against matrix metalloprotease-13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM30359
(BOC-piperidinyl glycine derivative, 34)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.5nM
pH: 7.5 T: 2°C
Assay Description:
Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM30359
(BOC-piperidinyl glycine derivative, 34)
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Affinity Data
IC50: 1.5nM
Assay Description:
Inhibition of MMP8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM30359
(BOC-piperidinyl glycine derivative, 34)
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Affinity Data
IC50: 1.5nM
Assay Description:
Inhibitory activity against matrix metalloprotease-8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM30359
(BOC-piperidinyl glycine derivative, 34)
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Affinity Data
IC50: 6.60nM
Assay Description:
In vitro inhibition of human matrix metalloprotease-9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM30359
(BOC-piperidinyl glycine derivative, 34)
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Affinity Data
IC50: 33.7nM
Assay Description:
In vitro inhibitory activity against matrix metalloprotease-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM30359
(BOC-piperidinyl glycine derivative, 34)
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Affinity Data
IC50: 1.37E+3nM
Assay Description:
In vitro inhibitory activity against matrix metalloprotease-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrilysin
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM30359
(BOC-piperidinyl glycine derivative, 34)
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Affinity Data
IC50: 3.66E+3nM
Assay Description:
Inhibitory activity against matrix metalloprotease-7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI