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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101734((1,4-Dioxa-spiro[4.5]dec-7-yl)-((R)-4'-methoxy-bip...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451194(CHEMBL2115084)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50:  630nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50:  3.78E+3nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed