Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Bone morphogenetic protein receptor type-1A
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50262016
(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.80nM
Assay Description:
Inhibition of ALK3 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50262016
(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of ALK1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-1
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50262016
(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
Inhibition of ALK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bone morphogenetic protein 4
(Homo sapiens (Human))
Harvard Medical School
Curated by
ChEMBL
Ligand
BDBM50262016
(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 55nM
Assay Description:
Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bone morphogenetic protein receptor type-1B
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50262016
(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 57nM
Assay Description:
Inhibition of ALK6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
TGF-beta receptor type-2
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50262016
(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 236nM
Assay Description:
Inhibition of TGFBR2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activin receptor type-1B
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50262016
(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.84E+3nM
Assay Description:
Inhibition of ALK4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5'-AMP-activated protein kinase subunit beta-1
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50262016
(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.26E+3nM
Assay Description:
Inhibition of AMPK (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
TGF-beta receptor type-1
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50262016
(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.33E+4nM
Assay Description:
Inhibition of ALK5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI