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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Merck Research Laboratories
Ligand
BDBM5420
(4-[6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
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Affinity Data
IC50: 37nM
pH: 7.4 T: 2°C
Assay Description:
Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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Article
PubMed
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Target
Bone morphogenetic protein 4
(Homo sapiens (Human))
Harvard Medical School
Curated by
ChEMBL
Ligand
BDBM5420
(4-[6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
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Affinity Data
IC50: 6.50E+3nM
Assay Description:
Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI