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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170202(4-(4-Methoxy-phenyl)-thiophene-2-carboxylic acid (...)
Affinity DataIC50:  230nMAssay Description:Inhibition of Matrix metalloproteinase-12 in pressence of 5 nM acetohydroximateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170202(4-(4-Methoxy-phenyl)-thiophene-2-carboxylic acid (...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170202(4-(4-Methoxy-phenyl)-thiophene-2-carboxylic acid (...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170202(4-(4-Methoxy-phenyl)-thiophene-2-carboxylic acid (...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170202(4-(4-Methoxy-phenyl)-thiophene-2-carboxylic acid (...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170202(4-(4-Methoxy-phenyl)-thiophene-2-carboxylic acid (...)
Affinity DataIC50: >1.01E+5nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170202(4-(4-Methoxy-phenyl)-thiophene-2-carboxylic acid (...)
Affinity DataIC50: >1.01E+5nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170202(4-(4-Methoxy-phenyl)-thiophene-2-carboxylic acid (...)
Affinity DataIC50: >1.01E+5nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed