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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098274(2-[4-(4-Methoxy-phenylethynyl)-benzenesulfonylamin...)
Affinity DataIC50:  28nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50098274(2-[4-(4-Methoxy-phenylethynyl)-benzenesulfonylamin...)
Affinity DataIC50:  115nMAssay Description:Inhibitory activity against recombinant human matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Gvk Biosciences

Curated by ChEMBL
LigandPNGBDBM50098274(2-[4-(4-Methoxy-phenylethynyl)-benzenesulfonylamin...)
Affinity DataIC50:  116nMpH: 7.4Assay Description:Inhibition of human matrix metalloproteinase-13 at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098274(2-[4-(4-Methoxy-phenylethynyl)-benzenesulfonylamin...)
Affinity DataIC50:  6.60E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098274(2-[4-(4-Methoxy-phenylethynyl)-benzenesulfonylamin...)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:Inhibition of human matrix metalloproteinase-1 at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed