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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi:  550nMAssay Description:Inhibition of human MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi:  900nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi:  900nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed