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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
hit in this display
Target
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Ligand
BDBM281058
(US10022352, Compound 319)
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Affinity Data
EC50: 39.1nM
Assay Description:
Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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