Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50:  25nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50:  59nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50:  729nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50320414(1-cyclopropyl-N-hydroxy-4-(4-(4-(4-methoxyphenyl)p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed